International
Tables for
Crystallography
Volume C
Mathematical, physical and chemical tables
Edited by E. Prince

International Tables for Crystallography (2006). Vol. C, ch. 3.2, p. 159

Table 3.2.3.1 

P. F. Lindleyb

Table 3.2.3.1| top | pdf |
Typical calculations of the values of VM and Vsolv for proteins

ProteinγB-CrystallinγD-CrystallinCeruloplasmin
Space group [P4_12_12 ] [P2_12_12_1 ] [P3_221 ]
Cell parameters (Å) 57.5 × 98.0 57.8 × 70.0 × 117.3 213.9 × 85.6
Molecular weight (kDa) 21 21 132
Z 8 4 6
VM3  Da−1) 1.93 5.65 4.95
Vsolv (%) 36 78 75
Resolution (Å) 1.5 2.0 3.1
In the case of γD-crystallin, the values for VM and Vsolv are abnormally high. A recalculation assuming two molecules per asymmetric unit, Za = 2, gives more reasonable values of VM = 2.83 Å3 Da−1 and Vsolv = 56%.