International Tables for Crystallography
Access to online content requires a licence
The preparation of heavy-atom derivatives of protein crystals for use in multiple isomorphous replacement and anomalous scattering International Tables for Crystallography (2006). Vol. F, ch. 12.1, pp. 247-255 [ doi:10.1107/97809553602060000679 ] Abstract In this chapter an introduction to the heavy-atom data bank is provided and strategies are reviewed that can be adopted in the preparation of heavy-atom derivatives of protein crystals for use in multiple isomorphous replacement and anomalous scattering. Topics covered include: heavy-atom derivatives and their complexes; amino acids as ligands; the protein chemistry of heavy-atom reagents; metal-ion replacement in metalloproteins; analogues of amino acids; and the use of the heavy-atom data bank to select derivatives. |
Access, prices and ordering
International Tables for Crystallography is available online as a full set of volumes through Wiley.
If you have already registered and are using a computer listed in your registration details, please email support@iucr.org for assistance.
About International Tables for Crystallography
International Tables for Crystallography is the definitive resource and reference work for crystallography. The multi-volume series comprises articles and tables of data relevant to crystallographic research and to applications of crystallographic methods in all sciences concerned with the structure and properties of materials.