International
Tables for Crystallography Volume F Crystallography of biological macromolecules Edited by M. G. Rossmann and E. Arnold © International Union of Crystallography 2006 |
International Tables for Crystallography (2006). Vol. F. ch. 21.3, p. 524
Figure 21.3.5.4
aUCLA–DOE Laboratory of Structural Biology and Molecular Medicine, UCLA, Box 951570, Los Angeles, CA 90095-1570, USA, bUCLA–DOE Laboratory of Structural Biology and Molecular Medicine, Department of Chemistry & Biochemistry, Molecular Biology Institute and Department of Biological Chemistry, UCLA, Los Angeles, CA 90095-1570, USA, and cUCLA–DOE Laboratory of Structural Biology and Molecular Medicine, Department of Chemistry & Biochemistry and Molecular Biology Institute, UCLA, Los Angeles, CA 90095-1569, USA |
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Figure 21.3.5.4
VERIFY3D profile plots of diphtheria toxin (DT) in three forms: open and closed monomers and the dimer. (a) DT open monomer (dashed), DT dimer (solid line). (b) DT closed monomer (dashed) and dimer (solid line). Notice that the hinge loop (residues 379–387) in the open monomer has a low profile score, and this structure is known to be unstable. The score is raised in the stable closed monomer and in the dimer. |