Family
|
Example
|
Protein structures solved
|
Reference
|
Arenaviridae
|
Lassa fever virus
|
None
|
|
Bunyaviridae
|
Hantavirus
|
None
|
|
Caliciviridae
|
Hepatitis E virus, Norwalk virus
|
None
|
|
Coronaviridae
|
Corona virus
|
None
|
|
Deltaviridae
|
Hepatitis D virus
|
Oligomerization domain of antigen
|
[1]
|
Filoviridae
|
Ebola virus
|
GP2 of membrane fusion glycoprotein
|
[2]
|
Flaviviridae
|
Dengue
|
NS3 protease
|
[3]
|
Hepatitis C
|
NS3 protease
|
[4], [5]
|
RNA helicase
|
[6]
|
Yellow fever
|
None
|
|
Tick-borne encephalitis virus
|
Envelope glycoprotein
|
[7]
|
Orthomyxoviridae
|
Influenza virus
|
Neuraminidase
|
[8]
|
Haemagglutinin
|
[9]
|
Matrix protein M1
|
[10]
|
Paramyxoviridae
|
Measles, mumps, parainfluenza, respiratory syncytial virus
|
None
|
|
Picornaviridae
|
Hepatitis A virus
|
3C protease
|
[11]
|
Poliovirus
|
Capsid
|
[12]
|
RNA-dependent polymerase
|
[13]
|
Rhinovirus
|
Capsid
|
[14]
|
3C protease
|
[15]
|
Echovirus
|
Capsid
|
[16]
|
Retroviridae
|
HIV
|
Capsid protein
|
[17]
|
Matrix protein
|
[18]
|
Protease
|
[19], [20], [21]
|
Reverse transcriptase
|
[22], [23], [47], [48], [49]
|
Integrase
|
[24]
|
gp120
|
[25]
|
NEF
|
[26]
|
gp41
|
[27]
|
Rhabdovirus
|
Rabies virus
|
None
|
|
Togaviridae
|
Rubella
|
None
|
|
Family
|
Example
|
Protein structures solved
|
Reference
|
Reoviridae
|
Rotavirus
|
None
|
|
Family
|
Example
|
Protein structures solved
|
Reference
|
Parvoviridae
|
B 19 virus
|
None
|
|
Family
|
Example
|
Protein structures solved
|
Reference
|
Adenoviridae
|
Adenovirus
|
Protease
|
[28]
|
Capsid
|
[29]
|
Knob domain of fibre protein
|
[30]
|
Hepadnaviridae
|
Hepatitis B
|
Capsid
|
[31]
|
Herpesviridae
|
Cytomegalovirus
|
Protease
|
[32], [33], [34]
|
Epstein–Barr virus
|
Domains of nuclear antigen 1
|
[35]
|
BCRF1
|
[36]
|
Herpes simplex
|
Protease
|
[37]
|
Thymidine kinase
|
[38]
|
Uracyl-DNA glycosylase
|
[39]
|
Core of VP16
|
[40]
|
Varicella zoster
|
Protease
|
[42]
|
Papovaviridae
|
Papillomavirus
|
DNA-binding domain of E2
|
[43]
|
Activation domain of E2
|
[44]
|
Poxviridae
|
Smallpox virus
|
None
|
|
Vaccinia virus (related to smallpox but non-pathogenic)
|
Methyltransferase VP39
|
[45]
|
Domain of topoisomerase
|
[46]
|
References: [1] Zuccola et al. (1998) ; [2] Weissenhorn et al. (1998) ; [3] Murthy et al. (1999) ; [4] Love et al. (1996) ; [5] Yan et al. (1998) ; [6] Yao et al. (1997) ; [7] Rey et al. (1995) ; [8] Varghese et al. (1983) ; [9] Wilson et al. (1981) ; [10] Sha & Luo (1997) ; [11] Allaire et al. (1994) ; [12] Hogle et al. (1985) ; [13] Hansen et al. (1997) ; [14] Rossmann et al. (1985) ; [15] Matthews et al. (1994) ; [16] Filman et al. (1998) ; [17] Worthylake et al. (1999) ; [18] Hill et al. (1996) ; [19] Navia, Fitzgerald et al. (1989) ; [20] Wlodawer et al. (1989) ; [21] Erickson et al. (1990) ; [22] Rodgers et al. (1995) ; [23] Ding et al. (1995) ; [24] Dyda et al. (1994) ; [25] Kwong et al. (1998) ; [26] Lee et al. (1996) ; [27] Chan et al. (1997) ; [28] Ding et al. (1996) ; [29] Roberts et al. (1986) ; [30] Xia et al. (1994) ; [31] Wynne et al. (1999) ; [32] Tong et al. (1996) ; [33] Qiu et al. (1996) ; [34] Shieh et al. (1996) ; [35] Bochkarev et al. (1995) ; [36] Zdanov et al. (1997) ; [37] Hoog et al. (1997) ; [38] Wild et al. (1995) ; [39] Savva et al. (1995) ; [40] Liu et al. (1999) ; [42] Qiu et al. (1997) ; [43] Hegde & Androphy (1998) ; [44] Harris & Botchan (1999) ; [45] Hodel et al. (1996) ; [46] Sharma et al. (1994) ; [47] Kohlstaedt et al. (1992 ); [48] Jacobo-Molina et al. (1993 ); [49] Ren et al. (1995 ).
|