The crystal structure of GlcNAc
Blake, C. C. F.,
Fenn, R. H.,
Johnson, L. N.,
Koenig, D. F.,
Mair, G. A.,
North, A. C. T.,
Oldham, J. W. H.,
Phillips, D. C.,
Poljak, R. J.,
Sarma, V. R. and
Vernon, C. A.,
International Tables for Crystallography
(2012).
Vol. F,
Section 25.1.4.2,
p.
[ doi:10.1107/97809553602060000899 ]
...
Proposals for the catalytic mechanism of lysozyme
Blake, C. C. F.,
Fenn, R. H.,
Johnson, L. N.,
Koenig, D. F.,
Mair, G. A.,
North, A. C. T.,
Oldham, J. W. H.,
Phillips, D. C.,
Poljak, R. J.,
Sarma, V. R. and
Vernon, C. A.,
International Tables for Crystallography
(2012).
Vol. F,
Section 25.1.4.5,
p.
[ doi:10.1107/97809553602060000899 ]
and E (or sites A and B, but this could be discarded because the trisaccharide complex was stable).
Close to the bond between sites D and E were two acid residues (Fig.
25.1.4.4) . As noted previously by members of the team, one of these, Glu35 ...
Structural studies on the biological function of lysozyme
Blake, C. C. F.,
Fenn, R. H.,
Johnson, L. N.,
Koenig, D. F.,
Mair, G. A.,
North, A. C. T.,
Oldham, J. W. H.,
Phillips, D. C.,
Poljak, R. J.,
Sarma, V. R. and
Vernon, C. A.,
International Tables for Crystallography
(2012).
Vol. F,
Section 25.1.4,
p.
[ doi:10.1107/97809553602060000899 ]
for Crystallography) How the structure of lysozyme was actually determined
25.1.4.1. Lysozyme substrates
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By the summer of 1964, the results for the structure determination of lysozyme were sufficiently promising ...
Low-resolution binding studies of lysozyme with GlcNAc and other sugars
Blake, C. C. F.,
Fenn, R. H.,
Johnson, L. N.,
Koenig, D. F.,
Mair, G. A.,
North, A. C. T.,
Oldham, J. W. H.,
Phillips, D. C.,
Poljak, R. J.,
Sarma, V. R. and
Vernon, C. A.,
International Tables for Crystallography
(2012).
Vol. F,
Section 25.1.4.3,
p.
[ doi:10.1107/97809553602060000899 ]
-acetylmuramic acid (GlcNAc-MurNAc – a gift from N. Sharon) (Fig.
25.1.4.2) .
Figure
25.1.4.2
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Inhibitor molecules of lysozyme (Blake et al., 1967). (a) N -acetylglucosamine; (b) N ...
Lysozyme substrates
Blake, C. C. F.,
Fenn, R. H.,
Johnson, L. N.,
Koenig, D. F.,
Mair, G. A.,
North, A. C. T.,
Oldham, J. W. H.,
Phillips, D. C.,
Poljak, R. J.,
Sarma, V. R. and
Vernon, C. A.,
International Tables for Crystallography
(2012).
Vol. F,
Section 25.1.4.1,
p.
[ doi:10.1107/97809553602060000899 ]
in Fig.
25.1.4.1 .
Figure
25.1.4.1
| top | pdf |
The cell-wall tetrasaccharide with the glycosidic bond that is hydrolysed by lysozyme indicated (Blake et al., 1967).
The structure ...
Binding studies of lysozyme with tri-N-acetyl-chitotriose, (GlcNAc)3, at 2 Å resolution
Blake, C. C. F.,
Fenn, R. H.,
Johnson, L. N.,
Koenig, D. F.,
Mair, G. A.,
North, A. C. T.,
Oldham, J. W. H.,
Phillips, D. C.,
Poljak, R. J.,
Sarma, V. R. and
Vernon, C. A.,
International Tables for Crystallography
(2012).
Vol. F,
Section 25.1.4.4,
p.
[ doi:10.1107/97809553602060000899 ]
for Crystallography) How the structure of lysozyme was actually determined
John Rupley visited the Royal Institution in July 1965. He brought with him a sample of tri- N -acetylchitotriose (Fig.
25.1.4.2), previously abbreviated as tri-NAG ...
