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 Results for DC.creator="D." AND DC.creator="M." AND DC.creator="Engelman" in section 19.4.5 of volume F
Solvent conditions
Engelman, D. M. and Moore, P. B.  International Tables for Crystallography (2012). Vol. F, Section 19.4.5.3, p. 580 [ doi:10.1107/97809553602060000870 ]
Solvent conditions 19.4.5.3. Solvent conditions Background arises from the incoherent scattering of hydrogen. Consequently, the use of high levels of D2O in the buffer improves the background, but may not be innocuous, since high levels of D2O have been seen to induce aggregation. In cases where complexes with labelled subunits are ...

Homogeneity and stability
Engelman, D. M. and Moore, P. B.  International Tables for Crystallography (2012). Vol. F, Section 19.4.5.2, p. 580 [ doi:10.1107/97809553602060000870 ]
Homogeneity and stability 19.4.5.2. Homogeneity and stability For measurements to be made, the samples must be transported to a neutron facility and measured for many hours. This requires stability in the usual biochemical sense, and proper experiments will include assays performed after the measurements. Damage from the neutrons themselves is minimal ...

Feasibility
Engelman, D. M. and Moore, P. B.  International Tables for Crystallography (2012). Vol. F, Section 19.4.5.1, p. 580 [ doi:10.1107/97809553602060000870 ]
... most often produced by growth of organisms in D2O (Moore & Engelman, 1976; Vanatalu et al., 1993), but strategies using chemical synthesis ... but still requires tests of homogeneity. References Moore, P. B. & Engelman, D. M. (1976). The production of deuterated E. coli. ...

Practical considerations
Engelman, D. M. and Moore, P. B.  International Tables for Crystallography (2012). Vol. F, Section 19.4.5, p. 580 [ doi:10.1107/97809553602060000870 ]
... most often produced by growth of organisms in D2O (Moore & Engelman, 1976; Vanatalu et al., 1993), but strategies using chemical synthesis ... the unlabelled regions via solvent adjustment. References Moore, P. B. & Engelman, D. M. (1976). The production of deuterated E. coli. ...

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