Crystallography is fortunate in having several curated databases of crystal structures. Different organizations validate, archive and disseminate structures of various types. This chapter describes the purpose and implementation of five databases, differing in scale and type of structure handled. The focus is on how the databases manage their content, and in particular how their various workflows are facilitated by the standardization enabled by the Crystallographic Information Framework. The five organizations and their major databases are: the Cambridge Crystallographic Centre and the Cambridge Structural Database of organic and metal--organic structures; the open-access Crystallography Open Database of inorganic, organic, metal--organic and organometallic compounds; Fachinformationszentrum (FIZ) Karlsruhe and the Inorganic Crystal Structure Database; the International Centre for Diffraction Data and the Powder Diffraction File; and the Bilbao Modulated Structures Database.